New Zealand Journal of Botany abstracts

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Analysing molecular sequences using consensus

WILLIAM H. E. DAY

Department of Computer Science
Memorial University of Newfoundland
St John's, NF A1C 5S7, Canada
F. R. McMORRIS
Department of Mathematics
University of Louisville
Louisville, KY 40292, U.S.A.

Abstract Although methods for discovering consensus sequences play a vital role in molecular biology, researchers often seem inattentive to the features and limitations of such methods, and so there are risks that criteria for discovering consensus sequences will be misused or misunderstood. To appreciate better the issues involved, methods for discovering consensus sequences are surveyed. Included are methods based on frequency thresholds, voting strategies, heuristics, neighbourhoods, and measures of inhomogeneity or information content.

Keywords alignment molecular sequences; consensus;

B93017 ; Received 2 February 1993; accepted 26 May 1993
New Zealand Journal of Botany, 1993, Vol. 31: 211-218
0028-825X/93/3103-0211 $2.50/0 © The Royal Society of New Zealand 1993

PDF file of entire paper: medium quality (654K); (scanned from paper original: notes about this process)

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